What Porcine Models Tell Us About Dermal Burn Healing

porcine tissue research pigsPorcine epithelium is an important tissue that is used in wound healing research, and is harvested from porcine models.

For example, a Brazilian study published in the November 20 edition of the International Journal of Pharmaceutics looked at porcine tissue and the treatment of burns.

“There are a range of products available which claim to accelerate the healing of burns; these include topical agents, interactive dressings and biomembranes,” the study’s authors wrote. “The aim of this study was to assess the effect of a gelatin-based membrane containing usnic acid/liposomes on the healing of burns in comparison to silver sulfadiazine ointment and duoDerme® dressing, as well as examining its quantification by high performance liquid chromatography.”

The researchers found that that a gelatin-based membrane containing usnic acid-loaded liposome improves dermal burn healing in the porcine model.

Animals treated with the membrane displayed development and maturation of granulation tissue and scar repair that was comparable to that produced by duoDerme®, and better than that produced by treatment with sulfadiazine silver ointment,” the study says, adding that those same animals showed increased collagen deposition” compared to two other study groups.

Past studies have shown how porcine models were effective in treating skin wounds in rats and in dealing with wound infections in the wake of liver transplants.

At Animal Biotech, we’re proud of the part we’ve played in making these sorts of discoveries over the last 26 years. We’re committed to providing the biomedical research world with high quality post mortem porcine tissues.

Contact us today to learn more about how we can help you make your next breakthrough.